Cascade volume is the margin. Model it, do not estimate it.
Single-site testing off a proband result is often the highest-margin work on a germline menu and the least modeled. It shows up as "other volume" in a spreadsheet, if it shows up at all.
What the model does with your menu
- Family cascade as derived demand: a fraction of one assay’s throughput becomes demand for another.
- Periodic re-analysis and re-contact costed as recurring work, not a one-time sign-out.
- Payer mix with denials, prior-auth and appeals: the realization gap that decides germline economics.
- The capital case stress-tested with tornado and Monte-Carlo sensitivity before you commit to it.
There is a fully-modeled hereditary / germline sample lab you can open right now. No signup, every number checkable, and a guided walkthrough that takes you to the answer.
Your archetype is a starting point, not a cage
If your lab sits on the border between two of these (most independent labs do) pick whichever is closest. Setup starts you with a lean set of capabilities for that archetype, and every other capability is a free switch you turn on until the model fits. Nothing is behind a tier, and nothing you turn on can be taken away by the choice you made on day one.
Built for the molecular lab: molecular IVD (PCR, syndromic panels, infectious disease) and clinical genomics. The same unit economics extend to broader-menu labs, but the molecular lab is who we build for.