Molecular labs are treated as cost centers because their real complexity and economics are invisible to the people who fund them.
Fulcrix makes them visible. It models your whole lab as one path: every step, instrument, handoff and integration. It costs each node, finds what’s actually limiting you, and grades every decision against what happened, so you can walk into the funding conversation with a number you can defend: every figure traces back to your own steps, costs, and actuals. It runs on the exports your LIMS and billing systems already produce, and replaces nothing.
Figures from our clinical sample lab, a modeled example, not your lab. Modeled estimates, not financial advice; validate independently.
We’re overhauling the product, so the public sample lab is offline for now. Request early access and the software sets your lab up on your own numbers, from the exports you already have. The first 3–5 labs join as Founding Labs and help shape the product. Pricing: coming soon. Available to US-based labs for now.
- Unit economics you can defend
- The binding constraint, costed
- Plan vs. actual over time
“Should we buy an automated liquid handler to take library prep off the bench?” Fulcrix models the manual prep step today: touch-time, FTE load, error/rework, the throughput it caps. Then the same workflow with the handler in place, against the capex. You get recovered $/mo, FTE freed, the new bottleneck, and payback / NPV / IRR. That is a board-ready business case instead of a gut call.
The first two work as soon as your lab is modeled, on your own numbers. The third takes a quarter: a decision has to be committed and the actuals have to arrive before anything can be graded, so until a founding lab completes a cycle, what we can show you there is a seeded example.
Each workspace is isolated by row-level security. No other customer can see your models, and we don’t use your numbers or models to train anything or sell them. Fulcrix models economics, not patient data: it is not designed for PHI, and inputs are aggregates (volumes, costs, reimbursement, turnaround). Keeping PHI out is your responsibility, and automated screens back you up on data import: spreadsheet and CSV uploads are checked for PHI-named columns and identifier-shaped values, and refuse on a hit: nothing is imported, and you are told the row and column to remove. 835 remittances are read in your browser, and only per-code totals are saved. On public pages we count anonymous visits; inside the product, usage analytics are pseudonymous and collected only with your consent, never your numbers, models, or identity. Decline or Do-Not-Track stops both.
And it stays yours to take: export your whole workspace to a file at any time, and if a subscription ever lapses your instance is snapshotted and recoverable for 90 days, so you don’t lose the model you built (after you terminate, the export window is 30 days, per the Terms).
Fulcrix is a decision-support and economics-modeling tool. It is not a clinical, diagnostic, or LIS system.
What you’ll need to validate your model
The complete input set. Start from a template, swap in your numbers (required + recommended), then reconcile one month of actuals to validate. Required inputs gate whether the economics can be trusted. A first answer from a template takes minutes. Your own lab takes about 10–15 minutes per workflow once the numbers are gathered; gathering them (volumes, reagent prices, staffing and rates) usually takes a few days across your team. Reconciling against your actuals is ongoing.
Start from a template
~2 min · no data neededPick the workflow you run (WGS, WES, targeted panel, RNA-seq, RT-qPCR, PGx), or start blank. Every step, instrument, cost, and turnaround comes pre-filled from cited public sources, so you get a first answer before entering anything.
Make it your lab
~10–15 min per workflow · once your numbers are gatheredReplace the template defaults with your numbers. These five are required before the economics can be trusted; the rest sharpen the picture.
- requiredMonthly volume· samples/mo for each workflow you run
- requiredReimbursement· a flat $/test, or a payer mix with each payer’s collection rate
- requiredSpecimen type· FFPE, blood, swab, cfDNA…; drives expected re-extraction/QC loss
- requiredKey reagent / kit cost· $/sample for your main reagent: library prep, master mix, or panel kit
- recommendedSequencing depth· NGS only: coverage × genome size, or Gb/sample (skip for PCR/qPCR assays)
- requiredLoaded labor rate· fully-burdened $/hour for your techs — the engine default is below loaded US market, so confirm yours
- recommendedTurnaround SLA target· the TAT you commit to per workflow; lights up SLA health
- recommendedStaffing & operating schedule· FTEs/hours per role and your operating days/hours (lab-level)
- optionalCompliance cost· proficiency testing + competency, $/mo (lab-level)
Reconcile against your actuals
~5 min per month of actuals · ongoingThis is what turns a reviewed model into one reconciled against reality. Import one month of real numbers and Fulcrix reports "modeled within X% of actual", a credibility check for your leadership team.
- requiredActual monthly COGS· total cost of goods for the month ($)
- requiredActual monthly tests· count of tests reported out that month
- requiredMonth· which month the actuals are from
Reviewed vs reconciled: entering your numbers (Stage 2) makes the model yours; reconciling actuals (Stage 3) shows how closely it tracks reality. Fulcrix is an informational modeling tool. Validate independently before any capital, staffing, or operational decision.